Wednesday, May 6, 2020

1.Describe The Mode Of Actions Of The Drugs That Interfere

1. Describe the mode of actions of the drugs that interfere with protein synthesis. Drugs that interfere with protein synthesis are derived from various actinomycetes species Streptomyces and Micromonospora. They inhibit protein synthesis by binding to one of the ribosomal subunits. Thus, disrupting protein synthesis as the ribosomes can no longer produce proteins. 2. Name and describe the actions of the aminoglycoside subgroup. Aminoglycosides are composed of one or more amino sugars and an aminocyclitol ring And the aminoglycosides are relatively broad spectrum drugs. They inhibit protein synthesis by binding to one of the ribosomal subunits. Streptomyces was one of the first aminoglycosides to be used and has been somewhat†¦show more content†¦If a patient is prescribed it, levels in the blood need to be constantly monitored. It is used to treat typhoid fever, brain abscesses and rickettsial and chlamydial infections that are resistant to other drugs. 5. Name and describe the uses of the newly developed classes of antibiotics. Fosfomycin trimethamine is a phosphoric acid agent used to treat UTIs caused by enteric bacteria. It works by inhibiting an enzyme needed for cell wall synthesis. Synercid used to treat Staphylococcus and Enterococcus infections. These infections often include endocarditis and surgical infections and they work by binding to the ribosomes. Daptomycin is a lipopeptide works against gram positive bacteria disrupting membrane functions. It is not used very often. Ketolides are similar to erythromycin and used to treat respiratory infections that are caused by macrolide resistant bacteria. Oxazolidinone works by inhibiting the initiation of protein synthesis as it interferes with the interaction between mRNA and the ribosomes. It is used to treat MRSA and vancomycin resistant Enterococcus. 6. Describe how polyenes work on fungal cells. Why is this drug safe for us? Polyenes work by binding to fungal membranes and cause the loss of selective permeability. The cells essentially start to leak their insides out. These drugs are specific for fungi because they bind to theShow MoreRelatedEpidemiology HIV Paper1382 Words   |  6 Pagesdefined by the Mayo Clinic as A chronic, potentially life-threatening condition which is caused by the human immunodeficiency virus (HIV). HIV damages the immune system, and interferes with the ability the body has to fight the disease causing organism (Mayo Clinic, 2014). HIV is an infection transmitted sexually. Another mode of transmission for HIV is by exposure to infected blood, or it could also be transmitted from the mother to the unborn child during the course of pregnancy, at childbirthRead MoreEssay on An Analysis of Human Immunodeficiency Virus1325 Words   |  6 PagesAIDS. Young people (15-24 year olds) account for half of all new HIV infections. More than 6,000 people become infected with HIV every day. 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